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Epitalon

Vial products ship as dry lyophilized material unless the product format explicitly states otherwise.

10mL Vial99%+ PurityAnti-Aging & Longevity
10mL Vial

Epitalon

Telomerase & longevity research peptide

$180.00
Research format / strength

Volume pricing

Per-unit price drops automatically as quantity increases.

Strength12+5+
100mg$180.00$171.00$162.00

Per-unit pricing at each quantity break, applied automatically at checkout.

Telomerase & longevity research peptide
Format
10mL Vial
Purity
≥99.0% by HPLC
Use
For laboratory and research purposes only. Not for human consumption, veterinary use, or medical applications.
Lot documentation

Certificate of Analysis

Your lot number is stamped on the base of the vial or bottle. Match it to the list to open the certificate for the exact material you received.

Lots on file
1
Laboratory
AxisPharm, LLC
View lot certificates
Published research

What the literature reports

Epitalon (AEDG tetrapeptide) is a synthetic pineal-related peptide examined in human cell culture for telomerase and telomere endpoints and in rodent lifespan and biomarker studies.

  1. In human somatic cell cultures, epithalon induced telomerase activity and telomere elongation.

    in vitro human somatic cell culture Khavinson et al., Bull Exp Biol Med, 2003 ↗
  2. In aging human fibroblast cultures, epithalon was reported to elongate telomeres and extend proliferative capacity beyond control cultures.

    in vitro aging fibroblast culture Khavinson et al., Bull Exp Biol Med, 2004 ↗
  3. In female SHR mice, long-term epitalon exposure increased maximum lifespan of the longest-lived cohort and reduced spontaneous leukemia incidence.

These summaries describe findings reported in published laboratory and clinical literature about this compound. They are provided for research context only. They are not claims about this product, and nothing here describes an intended use in humans or animals. This material is supplied strictly for laboratory research use.

Technical documentation

About Epitalon

Technical overview

synthetic pineal tetrapeptide

Epitalon, also called Epithalon or AEDG, is a short tetrapeptide with the sequence Ala-Glu-Asp-Gly. Research interest comes from pineal-peptide biology, cellular aging models, telomerase activity, gene expression, circadian regulation, and lifespan experiments in animals and cell systems. The evidence base includes many older and region-specific studies, so careful source reading matters.

Epitalon is not an FDA-approved drug product. Research-grade Epitalon is Research Use Only and is not for human consumption. Reported ranges below are drawn from experimental cell and animal contexts where dosing units can differ substantially from vial-based peptide math.

Mechanism of action

Epitalon is studied for effects on telomerase activation, telomere dynamics, chromatin state, antioxidant systems, and pineal-regulated gene expression. Cell studies report changes in telomerase activity and telomere length, while animal studies examine lifespan markers, tumor incidence, and aging biomarkers. The mechanism is not reducible to one receptor target; it is usually framed through gene regulation and peptide bioregulation hypotheses.

Research applications

  • telomerase activity
  • telomere biology
  • aging biomarkers
  • pineal peptide research
  • gene expression

Fields of active investigation, not claims. Investigation is not proof.

Epitalon is studied by aging biologists, peptide bioregulation researchers, cell-culture groups, and gerontology-focused pharmacologists. Translational reviewers usually distinguish cell and animal findings from human claims because the clinical evidence is limited and heterogeneous.

Amounts reported in the literature

What published research and laboratory protocols document. These describe what was studied — they are not instructions, recommendations, or a protocol for use.

Reported amount Frequency Route Research context
0.01 mcg – 10 mcg cell-culture exposure in vitro Human somatic cell studies of Epithalon telomerase activity
0.1 mcg – 1 mcg course-based animal protocols animal-study injection routes Animal aging biomarker studies with Epitalon

Handling and storage

Lyophilized Epitalon is commonly stored cold, dry, and protected from light; reconstituted research solutions are generally refrigerated and handled aseptically.

Notes on combined research

Epitalon is often discussed with longevity-oriented compounds, NAD+ biology, or mitochondrial peptides, but those combinations can turn a cellular-aging question into an uninterpretable multi-variable protocol. Research designs should define whether the endpoint is telomerase, circadian markers, oxidative stress, or lifespan-model biology before adding other compounds.

Analytical specifications

Purity ≥99.0% by HPLC
Format 10mL Vial
Physical form Lyophilized powder
Third-party laboratory AxisPharm, LLC
Lots with COA on file 1
Also referred to as Epithalon, Epithalone, AEDG, Ala-Glu-Asp-Gly
Reported half-life Not well established for practical human use; Epitalon literature focuses more on cellular and gene-expression outcomes than on clinical pharmacokinetics.

Identity and purity are documented per lot on the Certificate of Analysis for the material you receive. Lot, manufacture and expiry are stamped on the base of the vial or bottle.

Frequently asked questions

what is the dosage for Epitalon
Published Epitalon work includes cell-culture and animal-study exposures with different units. These are reference values, not personal dosing guidance.

how much bacteriostatic water for Epitalon
Research vials are often modeled with 1-2 mL reconstitution volumes. The right lab concentration depends on the experiment.

Epitalon dosage per day
Daily schedules discussed online often compress heterogeneous research into simple cycles. Literature-based content should cite the model, route, and endpoint.

Epitalon dosage chart
A responsible chart should separate in vitro concentration data, animal exposure, and vial concentration math rather than presenting one universal chart.

how long does Epitalon take
Cellular endpoints such as gene expression can be measured over short lab windows, while aging-model outcomes require longer study designs.

Epitalon half life
A practical human half-life is not well established in mainstream sources. Research often focuses on downstream cellular markers.

can Epitalon be stacked
It can be studied alongside other aging-biology variables, but stacking can make telomerase, redox, and circadian findings hard to attribute.

References

Every reference below resolves to an indexed paper. We would rather cite less and cite accurately.

Research use only

For laboratory and research purposes only. Not for human consumption, veterinary use, or medical applications. This product is not a drug, food, supplement or cosmetic, is not approved by the FDA, and is not intended to diagnose, treat, cure or prevent any disease. This page summarises published scientific literature; it is not medical advice and not a recommendation to use this compound. All handling must be performed by qualified personnel in a controlled laboratory environment.

Made in America. Documented lot by lot.

Most peptides sold in this category are imported in bulk, repackaged, and sold with no paperwork attached to the material in the bottle. Ours are synthesized in United States laboratories and every lot carries its own certificate.

Where is this material made?+
In United States laboratories. We buy from domestic synthesis rather than importing finished bulk from an overseas supplier and relabeling it. That is the reason we are able to name a specific laboratory, lot and test date for what you receive.
Why does a US laboratory matter?+
A domestic supply chain is shorter and documented end to end: identifiable facilities operating under US laboratory practice, and paperwork that follows one specific lot instead of a generic product description. It also means shorter transit and no repackaging between the laboratory and the customer.
What documentation comes with a lot?
A lot-specific Certificate of Analysis from an independent laboratory. The lot number is stamped on the base of the container — match it against the certificates listed on this page, or scan the QR code on the label, to open the report for the exact material shipped.
Where does my order ship from?+
Our United States facility, packed and dispatched domestically with tracking. Orders do not transit customs or get repackaged en route.