

Vial products ship as dry lyophilized material unless the product format explicitly states otherwise.
Epitalon
Telomerase & longevity research peptide
Volume pricing
Per-unit price drops automatically as quantity increases.
| Strength | 1 | 2+ | 5+ |
|---|---|---|---|
| 100mg | $180.00 | $171.00 | $162.00 |
Per-unit pricing at each quantity break, applied automatically at checkout.
Certificate of Analysis
Your lot number is stamped on the base of the vial or bottle. Match it to the list to open the certificate for the exact material you received.
- Lots on file
- 1
- Laboratory
- AxisPharm, LLC
What the literature reports
Epitalon (AEDG tetrapeptide) is a synthetic pineal-related peptide examined in human cell culture for telomerase and telomere endpoints and in rodent lifespan and biomarker studies.
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In human somatic cell cultures, epithalon induced telomerase activity and telomere elongation.
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In aging human fibroblast cultures, epithalon was reported to elongate telomeres and extend proliferative capacity beyond control cultures.
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In female SHR mice, long-term epitalon exposure increased maximum lifespan of the longest-lived cohort and reduced spontaneous leukemia incidence.
These summaries describe findings reported in published laboratory and clinical literature about this compound. They are provided for research context only. They are not claims about this product, and nothing here describes an intended use in humans or animals. This material is supplied strictly for laboratory research use.
About Epitalon
Technical overview
synthetic pineal tetrapeptide
Epitalon, also called Epithalon or AEDG, is a short tetrapeptide with the sequence Ala-Glu-Asp-Gly. Research interest comes from pineal-peptide biology, cellular aging models, telomerase activity, gene expression, circadian regulation, and lifespan experiments in animals and cell systems. The evidence base includes many older and region-specific studies, so careful source reading matters.
Epitalon is not an FDA-approved drug product. Research-grade Epitalon is Research Use Only and is not for human consumption. Reported ranges below are drawn from experimental cell and animal contexts where dosing units can differ substantially from vial-based peptide math.
Mechanism of action
Epitalon is studied for effects on telomerase activation, telomere dynamics, chromatin state, antioxidant systems, and pineal-regulated gene expression. Cell studies report changes in telomerase activity and telomere length, while animal studies examine lifespan markers, tumor incidence, and aging biomarkers. The mechanism is not reducible to one receptor target; it is usually framed through gene regulation and peptide bioregulation hypotheses.
Research applications
- telomerase activity
- telomere biology
- aging biomarkers
- pineal peptide research
- gene expression
Fields of active investigation, not claims. Investigation is not proof.
Epitalon is studied by aging biologists, peptide bioregulation researchers, cell-culture groups, and gerontology-focused pharmacologists. Translational reviewers usually distinguish cell and animal findings from human claims because the clinical evidence is limited and heterogeneous.
Amounts reported in the literature
What published research and laboratory protocols document. These describe what was studied — they are not instructions, recommendations, or a protocol for use.
| Reported amount | Frequency | Route | Research context |
|---|---|---|---|
| 0.01 mcg – 10 mcg | cell-culture exposure | in vitro | Human somatic cell studies of Epithalon telomerase activity |
| 0.1 mcg – 1 mcg | course-based animal protocols | animal-study injection routes | Animal aging biomarker studies with Epitalon |
Handling and storage
Lyophilized Epitalon is commonly stored cold, dry, and protected from light; reconstituted research solutions are generally refrigerated and handled aseptically.
Notes on combined research
Epitalon is often discussed with longevity-oriented compounds, NAD+ biology, or mitochondrial peptides, but those combinations can turn a cellular-aging question into an uninterpretable multi-variable protocol. Research designs should define whether the endpoint is telomerase, circadian markers, oxidative stress, or lifespan-model biology before adding other compounds.
Analytical specifications
| Purity | ≥99.0% by HPLC |
|---|---|
| Format | 10mL Vial |
| Physical form | Lyophilized powder |
| Third-party laboratory | AxisPharm, LLC |
| Lots with COA on file | 1 |
| Also referred to as | Epithalon, Epithalone, AEDG, Ala-Glu-Asp-Gly |
| Reported half-life | Not well established for practical human use; Epitalon literature focuses more on cellular and gene-expression outcomes than on clinical pharmacokinetics. |
Identity and purity are documented per lot on the Certificate of Analysis for the material you receive. Lot, manufacture and expiry are stamped on the base of the vial or bottle.
Frequently asked questions
what is the dosage for Epitalon
Published Epitalon work includes cell-culture and animal-study exposures with different units. These are reference values, not personal dosing guidance.
how much bacteriostatic water for Epitalon
Research vials are often modeled with 1-2 mL reconstitution volumes. The right lab concentration depends on the experiment.
Epitalon dosage per day
Daily schedules discussed online often compress heterogeneous research into simple cycles. Literature-based content should cite the model, route, and endpoint.
Epitalon dosage chart
A responsible chart should separate in vitro concentration data, animal exposure, and vial concentration math rather than presenting one universal chart.
how long does Epitalon take
Cellular endpoints such as gene expression can be measured over short lab windows, while aging-model outcomes require longer study designs.
Epitalon half life
A practical human half-life is not well established in mainstream sources. Research often focuses on downstream cellular markers.
can Epitalon be stacked
It can be studied alongside other aging-biology variables, but stacking can make telomerase, redox, and circadian findings hard to attribute.
References
Every reference below resolves to an indexed paper. We would rather cite less and cite accurately.
- Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties.
- Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells.
- Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice.
Research use only
For laboratory and research purposes only. Not for human consumption, veterinary use, or medical applications. This product is not a drug, food, supplement or cosmetic, is not approved by the FDA, and is not intended to diagnose, treat, cure or prevent any disease. This page summarises published scientific literature; it is not medical advice and not a recommendation to use this compound. All handling must be performed by qualified personnel in a controlled laboratory environment.
Made in America. Documented lot by lot.
Most peptides sold in this category are imported in bulk, repackaged, and sold with no paperwork attached to the material in the bottle. Ours are synthesized in United States laboratories and every lot carries its own certificate.


