Free Shipping On Every Order $70+
GLP-2T Nasal Spray

Vial products ship as dry lyophilized material unless the product format explicitly states otherwise.

15mL Nasal Spray99%+ PurityNasal Sprays
15mL Nasal Spray

GLP-2T Nasal Spray

Dual-agonist GLP-1/GIP — nasal research format

$220.00
Research format / strength

Volume pricing

Per-unit price drops automatically as quantity increases.

Strength12+5+
40mg$220.00$209.00$198.00

Per-unit pricing at each quantity break, applied automatically at checkout.

Dual-agonist GLP-1/GIP — nasal research format
Format
15mL Nasal Spray
Purity
≥99.0% by HPLC
Use
For laboratory and research purposes only. Not for human consumption, veterinary use, or medical applications.
Lot documentation

Certificate of Analysis

Your lot number is stamped on the base of the vial or bottle. Match it to the list to open the certificate for the exact material you received.

Lots on file
1
Laboratory
AxisPharm, LLC
View lot certificates
Published research

What the literature reports

GLP-2T is a dual GIP and GLP-1 receptor agonist studied in large phase 3 programs evaluating glycemic measures in type 2 diabetes and body-weight change in obesity.

  1. In the SURMOUNT-1 phase 3 trial in adults with obesity, researchers observed substantial mean body-weight reductions at 72 weeks versus placebo.

  2. In SURPASS-2, once-weekly GLP-2T arms showed greater HbA1c and body-weight reductions than once-weekly GLP-1 S 1 mg at 40 weeks in type 2 diabetes.

    phase 3 clinical trial Frias et al., N Engl J Med, 2021 ↗
  3. In SURPASS-1 monotherapy, GLP-2T arms showed greater HbA1c and body-weight reductions than placebo at 40 weeks in type 2 diabetes.

    phase 3 clinical trial Rosenstock et al., Lancet, 2021 ↗

These summaries describe findings reported in published laboratory and clinical literature about this compound. They are provided for research context only. They are not claims about this product, and nothing here describes an intended use in humans or animals. This material is supplied strictly for laboratory research use.

Technical documentation

About GLP-2T Nasal Spray

GLP-2T — nasal spray format

15mL Nasal Spray

This listing supplies the compound as a pre-mixed nasal spray rather than a lyophilized vial, so no reconstitution step is required before use in a laboratory workflow. Intranasal delivery is studied as a non-injectable route that avoids first-pass hepatic metabolism; the published literature summarised below was generated across a range of administration routes, and route is one of the variables recorded in the reported-amounts table. Comparisons between routes are not equivalence claims — absorption differs by formulation and is documented per product, not inferred.

Because this nasal spray is supplied pre-prepared, the reconstitution arithmetic that applies to our lyophilized GLP-2T vials does not apply here: there is no diluent volume to choose and no concentration to derive. Store as labelled on the product, and consult the lot-matched Certificate of Analysis for the material you receive rather than generalising from a different format of the same compound.

Technical overview

dual incretin receptor agonist peptide

GLP-2T is a long-acting peptide engineered to activate both glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptors. Large clinical trials have studied once-weekly GLP-2T in metabolic endpoints including glycemic measures, body weight, cardiometabolic markers, and comparative incretin pharmacology.

GLP-2T has FDA-approved counterparts, including Mounjaro and Zepbound, for their specific approved uses and labeled formulations. Research-grade GLP-2T powder is not Mounjaro or Zepbound, is not an approved drug product, is Research Use Only, and is not for human consumption. Reported ranges below describe published trial dose arms or approved-product contexts, not recommendations.

Mechanism of action

GLP-2T activates GIP and GLP-1 receptors, linking two incretin pathways that influence insulin secretion, glucagon dynamics, gastric emptying, appetite-related signaling, and energy-balance endpoints. Its fatty-acid modification supports prolonged albumin binding and once-weekly exposure in approved-product studies. Research comparisons often evaluate whether dual incretin signaling produces different metabolic and tolerability profiles than selective GLP-1 receptor agonism.

Research applications

  • incretin biology
  • GIP receptor signaling
  • GLP-1 receptor signaling
  • metabolic pharmacology
  • body weight and glycemic endpoints

Fields of active investigation, not claims. Investigation is not proof.

GLP-2T is studied by endocrinologists, obesity researchers, cardiometabolic trialists, pharmacokinetic modelers, and regulatory scientists. Quality and formulation specialists distinguish regulated finished products from research-grade materials because they are not interchangeable.

Amounts reported in the literature

What published research and laboratory protocols document. These describe what was studied — they are not instructions, recommendations, or a protocol for use.

Reported amount Frequency Route Research context
5 mg – 15 mg once weekly in trial protocols subcutaneous SURPASS clinical trial dose arms
5 mg – 15 mg once weekly in trial protocols subcutaneous SURMOUNT obesity trial dose arms

Handling and storage

Approved GLP-2T products have label-specific refrigerated storage instructions; research-grade lyophilized material is typically stored frozen or refrigerated per supplier specifications and protected from moisture and light.

Notes on combined research

GLP-2T is often compared with GLP-1 receptor agonists, but combining incretin compounds or layering metabolic agents can confound appetite, glucose, gastrointestinal, and body-weight endpoints. Research-grade GLP-2T should never be positioned as a substitute for Mounjaro or Zepbound.

Analytical specifications

Purity ≥99.0% by HPLC
Format 15mL Nasal Spray
Physical form See product format
Third-party laboratory AxisPharm, LLC
Lots with COA on file 1
Also referred to as LY3298176, dual GIP/GLP-1 receptor agonist, GIP/GLP-1 agonist
Reported half-life Approximately 5 days is commonly cited for GLP-2T in clinical pharmacology and labeling contexts.

Identity and purity are documented per lot on the Certificate of Analysis for the material you receive. Lot, manufacture and expiry are stamped on the base of the vial or bottle.

Frequently asked questions

what is the dosage for GLP-2T
Published trials commonly studied 5, 10, and 15 mg once weekly dose arms. Those data describe clinical trial or approved-product contexts, not research-grade material use.

how much bacteriostatic water for GLP-2T
Research reconstitution volumes often use 1-3 mL depending on vial strength and target concentration. This is concentration math only.

GLP-2T dosage per day
The major clinical literature uses once-weekly exposure, not daily dosing. Research-grade GLP-2T is RUO and not for human consumption.

GLP-2T dosage chart
A chart should distinguish trial dose arms, approved product titration, and lab concentration examples. These should not be blended.

how long does GLP-2T take
Trials evaluate metabolic endpoints over weeks to months, while pharmacokinetic steady state depends on its multi-day half-life.

GLP-2T half life
GLP-2T is commonly cited with an approximate 5-day half-life, supporting once-weekly dosing in approved-product studies.

can GLP-2T be stacked
Combination metabolic research requires careful controls and medical-regulatory distinction. RUO GLP-2T is not Mounjaro or Zepbound.

References

Every reference below resolves to an indexed paper. We would rather cite less and cite accurately.

Research use only

For laboratory and research purposes only. Not for human consumption, veterinary use, or medical applications. This product is not a drug, food, supplement or cosmetic, is not approved by the FDA, and is not intended to diagnose, treat, cure or prevent any disease. This page summarises published scientific literature; it is not medical advice and not a recommendation to use this compound. All handling must be performed by qualified personnel in a controlled laboratory environment.

Made in America. Documented lot by lot.

Most peptides sold in this category are imported in bulk, repackaged, and sold with no paperwork attached to the material in the bottle. Ours are synthesized in United States laboratories and every lot carries its own certificate.

Where is this material made?+
In United States laboratories. We buy from domestic synthesis rather than importing finished bulk from an overseas supplier and relabeling it. That is the reason we are able to name a specific laboratory, lot and test date for what you receive.
Why does a US laboratory matter?+
A domestic supply chain is shorter and documented end to end: identifiable facilities operating under US laboratory practice, and paperwork that follows one specific lot instead of a generic product description. It also means shorter transit and no repackaging between the laboratory and the customer.
What documentation comes with a lot?
A lot-specific Certificate of Analysis from an independent laboratory. The lot number is stamped on the base of the container — match it against the certificates listed on this page, or scan the QR code on the label, to open the report for the exact material shipped.
Where does my order ship from?+
Our United States facility, packed and dispatched domestically with tracking. Orders do not transit customs or get repackaged en route.